Produktinformation
- Relenza GG 167 4-Guanidino-2,4-dideoxy-2,3-didehydro-N-acetylneuraminic acid
Potent and selective inhibitor of influenza A and B sialidases. Zanamivir belongs to the class of drugs known as neuraminidase inhibitors. This compound is a sialic acid analogue that occupies viral neuraminidase active site, inhibits enzyme’s hydrolytic activity and cleavage of sialic acid residues from host cell surface glycans. It therefore prevents shedding newly produced virions from infected cell surface and reduces infection of surrounding cells. In in vitro studies with influenza A and B virus isolates, zanamivir inhibited the plaque formation by 50% in canine cells (MDCK) with concentrations between 0.004 and 0.014 μM and 0.02 and 16 μM, respectively.
Zanamivir hydrate is part of our Bio-X ™ Range. These products are aimed at life science researchers who need high quality ready to use products for assay development, screening or other R&D work. With a solubility datasheet and convenient vials, all of our Bio-X ™ products are in stock across our global warehouses for rapid delivery and ease of use.
Chemische Eigenschaften
Technische Anfrage zu: 3D-BZ164566 Zanamivir hydrate - Bio-X ™
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