N-(3,4-Dihydroxyphenethyl)acetamide

CAS: 2494-12-4

Ref. 3D-CAA49412

Produktinformation

• Name: N-(3,4-Dihydroxyphenethyl)acetamide
• Synonyme: NSC 314644, N-[2-(3,4-Dihydroxyphenyl)ethyl]acetamide, N-Acetyldopamine, Acetamide, N-[2-(3,4-dihydroxyphenyl)ethyl]-, Acetamide, N-(3,4-dihydroxyphenethyl)-

Beschreibung

N-(3,4-Dihydroxyphenethyl)acetamide is a histamine agonist that inhibits the production of proinflammatory cytokines such as tumor necrosis factor (TNF)-α and interleukin (IL)-6 by inhibiting 5-hydroxytryptamine (5-HT) concentrations. It has been shown to inhibit the growth of HL60 cells at a concentration of 10 μM. N-(3,4-Dihydroxyphenethyl)acetamide is also able to inhibit Cox-2 enzymatic activity in vitro and has been shown to be active in vivo against chronic colitis in mice. The optimum pH for N-(3,4-dihydroxyphenethyl)acetamide is 7.0 and its Michaelis-Menten kinetics are first order. This drug also has an affinity for fatty acids and dopamine receptors, which may contribute to its anti-inflammatory effects.

• Marke: Biosynth

Chemische Eigenschaften

• Molekulargewicht: 195.22 g/mol
• Formel: C₁₀H₁₃NO₃
• Reinheit: Min. 95%