2-Oxo-1-oxaspiro[4.5]decane-4-carboxylic acid

CAS: 2819-56-9

Ref. 3D-CAA81956

Produktinformation

• Name: 2-Oxo-1-oxaspiro[4.5]decane-4-carboxylic acid
• Synonyme: 1-Oxaspiro[4.5]decane-4-carboxylic acid, 2-oxo-, Butanedioic acid, (1-hydroxycyclohexyl)-, γ-lactone, Cyclohexanesuccinic acid, 1-hydroxy-, γ-lactone, NSC 25328

Beschreibung

2-Oxo-1-oxaspiro[4.5]decane-4-carboxylic acid is a nitrile that can be synthesized by decarboxylation of 4-chloro-2,6-dimethylaniline with nitrous acid and sulfuric acid. The intramolecular cyclization of methyl 2-(nitrobenzyl)malonate to the thiazole ring is catalyzed by a mixture of acetic anhydride and pyridine. The reaction is carried out at refluxing temperatures in a homogeneous solvent such as toluene or chloroform. This product can also be obtained from the reaction of 2,6-dimethylaniline with hydroxylamine hydrochloride in the presence of sodium hydroxide.

• Marke: Biosynth

Chemische Eigenschaften

• Molekulargewicht: 198.22 g/mol
• Formel: C₁₀H₁₄O₄
• Reinheit: Min. 95%