AM 281

CAS: 202463-68-1

Ref. 3D-CIA46368

Produktinformation

• Name: AM 281
• Marke: Biosynth

Beschreibung

AM281 is a cannabinoid receptor antagonist that binds to the CB1 cannabinoid receptor and blocks the effect of cannabinoids. AM281 has been shown to reduce the number of bowel disease-related symptoms in mice by reversing the up-regulation of toll-like receptors (TLRs) in the colon. AM281 also reduces inflammation and injury by inhibiting DPP-IV, an enzyme that destroys insulin, which leads to a synergistic effect on neurons in rats. AM281 has been shown to have a synergistic effect with DPP-IV inhibitors, leading to an increase in neuronal activity and improved memory retention. It is used for brain injury research, as it blocks the effects of cannabinoids on hippocampal neurons.

Chemische Eigenschaften

• Molekulargewicht: 557.21 g/mol
• Formel: C₂₁H₁₉Cl₂IN₄O₂
• Reinheit: Min. 95%