Lipid A (Salmonella)

CAS: 100742-61-8

Ref. 3D-CLP-24008-S

Produktinformation

• Name: Lipid A (Salmonella)
• Synonyme: 2-Deoxy-6-O-{2-deoxy-2-[(R)-3-(dodecanoyloxy)tetradecanoylamino]-3-O-[(R)-3-(tetradecanoyloxy)tetradecanoyl]-β-D-glucopyranosyl}-2-[ (R)-3-(hexadecanoyloxy)tetradecanoylamino]-3-O-[(R)-3-hydroxytetradecanoyl]-α-D-glucopyranose 1,4'-diphosphate
• Marke: Biosynth
• Beschreibung: Lipid A is a bacterial endotoxin that activates macrophages and dendritic cells, which in turn activate T-cells. It is a ligand for the CD14 receptor, which is a pattern recognition molecule found on macrophages and dendritic cells. Lipid A also binds to the Toll-like receptor 4 (TLR4) on host cells, initiating an inflammatory response. Lipid A has been used as a research tool to study cell biology related to activation of macrophages and dendritic cells leading to cytokine production. This activator has also been used as a ligand in antibody studies, ion channel studies, protein interactions, pharmacology experiments with peptides, and life science research.

Chemische Eigenschaften

• Molekulargewicht: 2,036.8 g/mol
• Formel: C₁₁₀H₂₀₈N₂O₂₆P₂
• Reinheit: Min. 95%