Dengue Virus Envelope Domain III Mouse Monoclonal Antibody

Ref. 3D-CM1266

Produktinformation

• Name: Dengue Virus Envelope Domain III Mouse Monoclonal Antibody

Beschreibung

This mouse monoclonal antibody targets domain III of the dengue virus envelope protein. The envelope protein is made up of the three domains, I, II and III and is involved in host cell receptor-mediated endocytosis and fusion. Domain II and III are primary targets for neutralizing antibody formation and so an ideal target for vaccine and treatment development.The Dengue virus causes the human disease, dengue fever. The dengue virus was first isolated by Ren Kimura and Susuma Hotta while studying blood samples of patients taken during the 1943 dengue epidemic in Nagasaki, Japan. It is transmitted to humans primarily via the Aedes aegypti and Aedes albopicto female mosquitoes which acquire the virus while feeding on the blood of an infected person. Although this virus can inflict asymptomatic or mild symptoms in patients, it can lead to severe infectious such as dengue hemorrhagic fever, also known as dengue shock syndrome.

• Marke: Biosynth