JNJ-54175446

CAS: 1627902-21-9

Ref. 3D-CQC90221

Produktinformation

• Name: JNJ-54175446
• Marke: Biosynth
• Beschreibung: JNJ-54175446 is a novel antidepressant drug that has a high uptake in the brain. It is an investigational drug that has been shown to have a rapid onset of action and to be effective across multiple depression symptom domains, including mood, anxiety, and cognitive symptoms. JNJ-54175446 binds to the serotonin transporter (SERT) with higher affinity than other antidepressants, which may contribute to its rapid onset of action. The compound also penetrates the blood-brain barrier more easily than other antidepressants and does not show signs of tolerance or withdrawal when used for up to 12 weeks. Clinical studies have shown that JNJ-54175446 has pharmacokinetic properties suitable for once-daily administration. In addition, this drug has been shown to increase levels of brain-derived neurotrophic factor (BDNF) in rats and mice, as well as microglia cells in animal models. This suggests that JNJ-54175446 may have beneficial effects on the brain's microenvironment

Chemische Eigenschaften

• Molekulargewicht: 440.8 g/mol
• Formel: C₁₈H₁₃ClF₄N₆O
• Reinheit: Min. 95%