CRAMP-18

Ref. 3D-CRB1000041

Produktinformation

• Name: CRAMP-18
• Synonyme: H-GEKLKKIGQKIKNFFQKL-OH
• Marke: Biosynth
• Beschreibung: Cathelicidin-related anti-microbial peptide (CRAMP), is the mouse homologue of the human LL-37 antimicrobial peptide and shares 67% sequence identity with LL-37.CRAMP-18 is the anti-bacterial sequence derived from CRAMP, it possesses potent anti-bacterial activity against Gram-positive and Gram-negative bacterial strains with no haemolytic activity. As well as displaying direct anti-microbial activity, CRAMP-18 also binds to lipopolysaccharide (LPS) to neutralise LPS activity.CRAMP is a cationic peptide, encoded for by the Camp gene and is highly expressed in bone marrow. Its expression is up-regulated by infectious and inflammatory signals and it is secreted by cells such as neutrophils, epithelial cells, and macrophages.

Chemische Eigenschaften

• Molekulargewicht: 2,147.61 g/mol