Produktinformation
Name:Pseudin-2
Synonyme:
- H-GLNALKKVFQGIHEAIKLINNHVQ-OHGLNALKKVFQGIHEAIKLINNHVQ-acidH-Gly-Leu-Asn-Ala-Leu-Lys-Lys-Val-Phe-Gln-Gly-Ile-His-Glu-Ala-Ile-Lys-Le u-Ile-Asn-Asn-His-Val-Gln-OHE pinecidin-1 prepropeptide
Marke:Biosynth
Beschreibung:Pseudin-2 (Ps) is one of the four pseudin peptides isolated from the skin of the paradoxical frog Pseudis-paradoxa. Pseudins are structurally related, cationic, amphipathic, a-helical anti-microbial peptides (AMP) that share sequence homology with an apoptosis regulating protein. Pseudin-2 is the most abundant and potent of the four pseudins.Pseudin-2 is active against Escherichia coli (with minimum inhibitory concentrations (MIC) of 2.5 mM), Staphylococcus aureus (MIC: 80 mM), and Candida albicans (MIC: 130 mM). Pseudin-2 also has low haemolytic activity against human erythrocytes (the concentration of Pseudin-2 producing 50% haemolysis: >300 mM).In addition to its anti-microbial properties, pseudin-2 has also been shown to stimulate insulin release and may be useful as a therapy for type 2 diabetes. This peptides has a non-amidated C-terminal end, as per the naturally occurring pseudin-2.
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Chemische Eigenschaften
Molekulargewicht:2,684 g/mol
Farbe/Form:Powder