PAR-4 Agonist (Human)

Ref. 3D-CRB1000558

Produktinformation

• Name: PAR-4 Agonist (Human)
• Synonyme: H-GYPGQV-NH2

Beschreibung

Protease activated receptors (PARs) are a distinctive four-member family of seven transmembrane G protein-coupled receptors (GPCRs) widely expressed in inflammatory cells. PARs are cleaved by certain serine proteases to expose a tethered ligand domain, this ligand domain then binds to and activates the receptors to initiate multiple signalling cascades. These PAR-activating proteases therefore represent PAR agonists. This PAR-4 agonist peptide represents the N-terminal sequence of the 'tethered ligand' and is therefore capable of activating the receptor independently of N-terminal proteolysis.

• Marke: Biosynth

Chemische Eigenschaften

• Molekulargewicht: 618.3 g/mol
• Farbe/Form: Powder