PTH (1-34) human

Ref. 3D-CRB1000854

Produktinformation

• Name: PTH (1-34) human
• Synonyme: H-SVSEIQLMHNLGKHLNSMERVEWLRKKLQDVHNF-OHPTH 1-34Parathyroid Hormone 1-34SVSEIQLMHNLGKHLNSMERVEWLRKKLQDVHNF-acidH-Ser-Val-Ser-Glu- Ile-Gln-Leu-Met-His-Asn-Leu-Gly-Lys-His-Leu-Asn-Ser-Met-Glu-Arg- Val-Glu-T rp-Leu-Arg-Lys-Lys-Leu-Gln-Asp-Val-His-Asn-P

Beschreibung

PTH 1-34, is a biologically active peptide fragment of parathyroid hormone (PTH). PHT 1-34 has been shown to enhance bone fracture healing by promoting osteogenesis. PTH 1-34 also has chondrogenic properties.PTH is an 84-amino-acid polypeptide hormone (PTH 1-84) which is secreted by the parathyroid glands along with its fragments (such as PTH 1-34 and PTH 7-84). PTH increases calcium and decrease phosphate levels in the blood and the abundance of PTH-derived peptides is regulated by blood calcium levels. PTH inhibits the bone growth-promoting activity of osteoblasts and induces osteoclasts to resorb bone and release calcium and phosphate ions into the blood. PTH binds to and activates the receptor parathyroid hormone receptor 1 (PTHR1). PTHR1 is a G-protein-coupled receptor (GPCR) which regulates mineral ion homeostasis, bone turnover and skeletal development.

• Marke: Biosynth

Chemische Eigenschaften

• Molekulargewicht: 4,115.1 g/mol
• Farbe/Form: Powder