PYK2 peptide substrate

Ref. 3D-CRB1000915

Produktinformation

• Name: PYK2 peptide substrate
• Synonyme: H-AGAGSIESDIYAEIPDETC-NH2AGAGSIESDIYAEIPDETC-amideH-Ala-Gly-Ala-Gly-Ser-Ile-Glu-Ser-Asp-Ile-Tyr-Ala-Glu-Ile-Pro-Asp-Glu-Thr-Cys-NH 2
• Marke: Biosynth
• Beschreibung: Substrate for proline-rich tyrosine kinase 2 (Pyk2)- can be used for substrate phosphorylation assays. Pyk2 is a member of the focal adhesion kinase (FAK) subfamily of cytoplasmic tyrosine kinases. Pyk2 is also known as: calcium-dependent tyrosine kinase (CADTK)- cellular adhesion kinase β- related adhesion focal tyrosine kinase (RAFTK)- or FAK2.Pyk2 functions as a scaffold protein, and it interacts with cytoplasmic proteins at focal adhesion sites to integrate different environmental signals. Pyk2 is activated by several stimuli, including elevated intracellular calcium levels, protein kinase C activation, and exposure to stress factors. Recently, Pyk2 has become a potentially important new therapeutic target or prognostic marker because overexpression of Pyk2 has been found in many human tumours.

Chemische Eigenschaften

• Molekulargewicht: 1,938.9 g/mol
• Reinheit: Min. 95%