GLP-1 (9-36) amide

CAS: 161748-29-4

Ref. 3D-CRB1000982

Produktinformation

• Name: GLP-1 (9-36) amide
• Synonyme: H-EGTFTSDVSSYLEGQAAKEFIAWLVKGR-NH2EGTFTSDVSSYLEGQAAKEFIAWLVKGR-amideH-Glu-Gly-Thr-Phe-Thr-Ser-Asp-Val-Ser-Ser-Tyr-Leu-Glu-Gly-Gln- Ala-Ala-Lys-Glu-Phe-Ile-Ala-Trp
• Marke: Biosynth

Beschreibung

Natural cleavage product of GLP-1 which, unlike GLP-1, does not affect either insulin secretion or glucose homeostasis.  GLP-1(9-36) has low affinity for, and acts as an antagonist to, the GLP-1 receptor.GLP-1 (9-36) does however display unique biological activities such as beneficial cardiovascular effects and reducing the production of reactive oxygen species (ROS). GLP-1 (9-36) also exerts important physiological effects on neuronal plasticity in the hippocampus, and inhibits chemokine-induced migration of human CD4-positive lymphocytes.GLP-1 (9-36) is formed from the breakdown of biologically active but highly unstable GLP-1 (7-36) amide by the ubiquitous serine protease, dipeptidyl peptidase-IV (DPP-IV).

Chemische Eigenschaften

• Molekulargewicht: 3,087.6 g/mol
• Farbe/Form: Powder