Intracellular Sigma Peptide

Ref. 3D-CRB1001355

Produktinformation

• Name: Intracellular Sigma Peptide
• Synonyme: H-GRKKRRQRRRCDMAEHMERLKANDSLKLSQEYESI-NH2GRKKRRQRRRCDMAEHMERLKANDSLKLSQEYESI-amideH-Gly-Arg-Lys-Lys-Arg-Arg-Gln-Arg-Arg-Arg-Cys-As p-Met-Ala-Glu-His-Met-Glu-Arg-Leu-Lys-Ala- Asn-Asp-Ser-Leu-Lys-Leu-Ser-Gln-Glu-Tyr-Glu-Ser-Ile-NH2

Beschreibung

Intracellular Sigma peptide is a membrane-permeable peptide mimetic of protein tyrosine phosphatase sigma (PTPσ) wedge. PTPσ is a neural receptor that binds with very high affinity to chondroitin sulfate proteoglycans (CSPGs). Inhibition of this interaction has been shown to promote regeneration of damaged nerves and improve nerve function in animal models. ISP has a protein transduction domain from HIV's trans-activating regulatory protein (Tat). This domain allows facilitates membrane-penetration.

• Marke: Biosynth

Chemische Eigenschaften

• Molekulargewicht: 4,316.2 g/mol