M12 muscle-homing peptide

Ref. 3D-CRB1001635

Produktinformation

• Name: M12 muscle-homing peptide
• Synonyme: H-RRQPPRSISSHP-OH
• Marke: Biosynth
• Beschreibung: Gene therapy is potentially an ideal treatment for muscle tissue myopathies but targeting remains an issue. The large volume of muscle in the body versus the requirement for tissue-specificity is of particular concern. This heptapeptide has been shown to preferentially bind myofibers and thus can be used to study targeting of peptide/gene- delivery to muscle tissue. Research into gene therapy of Duchenne muscular dystrophy (DMD) and Spinal muscular atrophy (SMA) has been of particular interest with muscle targeting peptides.- This product has been shown to orientate to muscle and heart tissue and when conjugated to a phosphorodiamidate morpholino oligomer (PMO)-increases dystrophin expression by 25%. This product already shows ideal placement to continue cardiac research to overcome some of these issues.

Chemische Eigenschaften

• Molekulargewicht: 1,416.8 g/mol
• Farbe/Form: Powder