Suc-LLVY-[AMC]

Ref. 3D-CRB1100485

Produktinformation

• Name: Suc-LLVY-[AMC]
• Synonyme: Suc-LLVY-[AMC]H-Leu-Leu-Val-Tyr-[AMC], where AMC is 7-amino-4-methylcoumarin

Beschreibung

Fluorogenic substrate peptide of the 20S proteasome. In its intact state this peptide is non-fluorescent, however when aminomethylcoumarin (AMC) is released upon hydrolysation, fluorescence can be detected. This peptide is therefore a useful tool for analysing the activity of the 20S proteasome as well as other chymotrypsin-like proteases and calpains. This peptide is also a substrate for chymase, papain, carboxypeptidase Y, proteinase yscE (kexin) and ingensin.AMC is a fluorescent dye with excitation maxima at around 360 nm and emission maxima at around 450 nm. AMC can be excited with a mercury lamp and observed using a UV filter set.

• Marke: Biosynth

Chemische Eigenschaften

• Molekulargewicht: 763.4 g/mol