Suc-LLVY-[Rh110]-[D-Pro]

Ref. 3D-CRB1100533

Produktinformation

• Name: Suc-LLVY-[Rh110]-[D-Pro]
• Synonyme: HO-Suc-LLVY-[Rho-110]-(dP)
• Marke: Biosynth
• Beschreibung: Fluorogenic substrate peptide of the 20S proteasome. In its intact state this peptide is non-fluorescent, however when Rhodamine fluorophore is released upon hydrolysation, fluorescence can be detected. This peptide is therefore a useful tool for analysing the activity of the 20S proteasome as well as other chymotrypsin-like proteases and calpains. This peptide is also a substrate for chymase, papain, carboxypeptidase Y, proteinase yscE (kexin) and ingensin.The presence of the D-proline residue on the C terminal of the rhodamine molecule ensures one directional rhodamine cleavage which simplifies fluorescence studies. Rhodamine 110 is a laser grade fluorescent dye with excitation maxima at 496 nm and emission maxima at 522 nm.

Chemische Eigenschaften

• Molekulargewicht: 1,015.5 g/mol