[5-FAM]-SRC Substrate Peptide

Ref. 3D-CRB1100604

Produktinformation

• Name: [5-FAM]-SRC Substrate Peptide
• Synonyme: 5fam-KVEKIGEGTYGVVYK-OH
• Marke: Biosynth
• Beschreibung: Substrate peptide for Scr, tyrosine kinase, for use in in vitro assays for Src activity.Src is a member of the Src Family tyrosine Kinases (SFKs), a large cytosolic, non-receptor, kinase family that controls multiple signalling pathways in animal cells. Src is a tyrosine kinase proto-oncogene and elevated levels of Src protein are seen in different tumours including: breast- lung- thyroid- glioblastoma- colorectal- pancreatic- prostate- gastric- biliary tract and skin cancer. Src levels are often associated with tumour progression, metastasis, and a poor clinical outcome and therefore Src has been investigated as a therapeutic target.Peptide is labelled with an N-terminal 5-carboxyfluorescein (5-FAM), a widely used green fluorescent tag.

Chemische Eigenschaften

• Molekulargewicht: 2,027.94 g/mol