CHKtide dual Heavy

Ref. 3D-CRB1300974

Produktinformation

• Name: CHKtide dual Heavy
• Synonyme: H-KKKV^SRSGLYRSPSMPENL^NRPR-OHKKK-[U-13C5,15N-Val]-SRSGLYRSPSMPEN-[U-13C6,15N-Leu]-NRPR-acidH-Lys-Lys-Lys-[U-13C5,15N-Val]-Ser-Arg -Ser-Gly-Leu-Tyr-Arg-Ser-Pro-Se r-Met-Pro-Glu-Asn-[U-13C6,15N-Leu]-Asn-Arg-Pro-Arg-OH

Beschreibung

CHKtide is a synthetic peptide substrate for checkpoint kinase 1 and 2 (CHK1/CHK2) as well as salt-inducible kinase (SIKs), for use in kinase assays. CHKtide has been derived from CDC25C which is phosphorylated by CHK1/CHK2 in one of the DNA repair pathways. SIKs are serine/threonine kinases that are part of a complex network that regulate sodium homeostasis and blood pressure.The valine residue at position 4 has been isotopically labelled with carbon-13(5) and nitrogen-15(1) and the leucine residue at position 19 has been isotopically labelled with carbon-13(6) and nitrogen-15(1). This isotopic labelling gives this peptide a mass increase of 13 compared to the unlabelled peptide.

• Marke: Biosynth

Chemische Eigenschaften

• Molekulargewicht: 2,712.5 g/mol
• Reinheit: Min. 95%
• Farbe/Form: Powder