Phosphorylated CHKtide Heavy

Ref. 3D-CRB1300976

Produktinformation

• Name: Phosphorylated CHKtide Heavy
• Synonyme: H-KKKV^(pS)RSGLYRSPSMPENLNRPR-OHKKK-[U-13C5,15N-Val]-[pS]-RSGLYRSPSMPENLNRPR-acidH-Lys-Lys-Lys-[U-13C5,15N-Val]-[pSer]-Arg-Ser-Gly -Leu-Tyr-Arg-Ser-Pro-Ser-Met-Pro- Glu-Asn-Leu-Asn-Arg-Pro-Arg-OH
• Marke: Biosynth
• Beschreibung: CHKtide is a synthetic peptide substrate for checkpoint kinase 1 and 2 (CHK1/CHK2) as well as salt-inducible kinase (SIKs) for use in kinase assays. CHKtide has been derived from CDC25C which is phosphorylated by CHK1/CHK2 in one of the DNA repair pathways. SIKs are serine/threonine kinases that are part of a complex network that regulate sodium homeostasis and blood pressure.The serine residue at position 5 has been phosphorylated and the valine residue at positon 4 has been isotopically labelled with carbon-13(5) and nitrogen-15(1).

Chemische Eigenschaften

• Molekulargewicht: 2,785.5 g/mol
• Reinheit: Min. 95%
• Farbe/Form: Powder