Apolipoprotein B-100 (APOB100) (3764-3772) Heavy

Ref. 3D-CRB1301567

Produktinformation

• Name: Apolipoprotein B-100 (APOB100) (3764-3772) Heavy
• Synonyme: H-FPEVDVL^TK-OH

Beschreibung

Apolipoprotein B-100 (apoB-100) is a highly expressed human protein, which is targeted by T- and B-cell immune responses in a subgroup of Lyme arthritis (LA) patients. ApoB-100 is present at high levels in the joint fluid of these patients. The high levels of apoB-100 in joints may lead to antigen presentation of apoB-100 peptides by human leukocyte antigen (HLA)-DR molecules, and to T- and B-cell responses to the protein making this protein a novel autoantigen. HLA-DR-presented peptides of apoB-100 have been shown to be immunoreactive.Lyme arthritis (LA) is a late manifestation of infection with the tick-borne spirochete,-Borrelia burgdorferi.The leucine residue at position seven of this peptide is isotopically labelled with carbon-13 (6) and nitrogen-15 (1), giving this peptide a mass increase of 7 compared to the unlabelled peptide.

• Marke: Biosynth

Chemische Eigenschaften

• Molekulargewicht: 1,053.6 g/mol
• Reinheit: Min. 95%