Anti-GLT-1 antibody - 1mg/mL

Ref. 3D-CRB2005049

Produktinformation

• Name: Anti-GLT-1 antibody - 1mg/mL

Beschreibung

Glutamate transporter 1 (GLT-1) is the major glutamate transporter in the brain, and is predominantly expressed in astrocytes, but at lower levels also in excitatory terminals. GLT-1 is best understood for its critical role in preventing neuronal excitotoxicity and brain seizures in the central nervous system (CNS). Maintaining the correct level of extracellular glutamate is crucial for neuronal transmission and network activity.

Glutamate uptake function allows GLTs/EAATs to terminate and shape excitatory synaptic transmission, and prevent neuronal excitotoxicity.Increasing evidence argues that GLT-1 also modulates, and is modulated by, metabolic processes that influence glucose homeostasis.

Data: Western blot analysis of rat brain preparation.
Lane 1: Rat brain preparation (20µg).
Secondary: Goat anti-rabbit IgG conjugated to HRP dilution 1:5000.

• Marke: Biosynth