Anti-GSK-3β antibody - 0.5mg/mL

Ref. 3D-CRB2005219

Produktinformation

• Name: Anti-GSK-3β antibody - 0.5mg/mL
• Marke: Biosynth
• Beschreibung: Glycogen Synthase Kinase 3 beta (GSK3β) is a multifunctional serine/threonine kinase widely expressed in most mammalian cells. GSK3β is highly active under basal conditions and acts downstream of phosphoinositide 3-kinase (PI3K) signalling. PI3K activation results in Akt phosphorylation and the subsequent phosphorylation of GSK3β at serine-9 and its inactivation. GSK3β in turn activates the production of pro-inflammatory cytokines including IL-1β, IL-6, IL-12, IL-17, TNFα and IFNγ, and supresses the production of IL-10, IL-1Ra, and IFNβ by immune cells.