Anti-POLDIP3 antibody - 2mg/mL

Ref. 3D-CRB2005743

Produktinformation

• Name: Anti-POLDIP3 antibody - 2mg/mL

Beschreibung

POLDIP3 is preferentially associated with CBC-bound spliced mRNA-protein complexes during the initial round of mRNA translation. POLDIP3 is deposited at the exon junction during pre-mRNA splicing. It becomes part of the exon junction complex (EJC), which then facilitates the recruitment of S6K1 to the spliced RNA to boost the translation efficiency of the spliced mRNA. In addition, POLDIP3 is involved in nuclear mRNA export mediated by association with the TREX complex.

POLDIP3 interacts with DNA polymerase Pol ÎŽ and PCNA depending on its modifications. This creates a distinct regulatory role for POLDIP3 during DNA synthesis.

• Marke: Biosynth