AF488 Anti-Lamin A/C antibody - 0.57mg/mL

Ref. 3D-CRB2115011

Produktinformation

• Name: AF488 Anti-Lamin A/C antibody - 0.57mg/mL
• Synonyme: Alexa Fluor ® 488 Anti-Lamin A/C antibod

Beschreibung

Nuclear lamin proteins (lamin A, B and C) form a complex structural scaffold, called the nuclear lamina, which is associated with the inside of the nuclear envelope. Lamins bind to a huge number of nuclear protein complexes and are involved in several processes, including chromatin organisation, gene regulation, genome stability, nuclear and cytoskeletal organisation, mechanical stability, differentiation, and tissue-specific functions. Mutations in lamin proteins result in laminopathies such as muscular dystrophy and the accelerated aging condition, Hutchinson-Gilford progeria. This antibody recognises human lamin A and C in both Western blots and immunohistochemistry with a strong signal and low background noise, and has an AF488 dye conjugated to it. AF488 is a popular, bright green, PH-stable fluorescent dye.

• Marke: Biosynth