5-Bromo-8-fluoroquinoline-7-boronic acid

CAS: 2377606-20-5

Ref. 3D-CVD60620

Produktinformation

• Name: 5-Bromo-8-fluoroquinoline-7-boronic acid

Beschreibung

5-Bromo-8-fluoroquinoline-7-boronic acid is a nucleotide analogue that has been used as a sequencing probe to study the nucleic acids of E. coli and other bacteria. 5-Bromo-8-fluoroquinoline-7-boronic acid is an analog of guanosine, which binds to RNA polymerase, preventing transcription and replication. The high frequency of human activity has been shown using a patch clamp technique on human erythrocytes. This active form is metabolized through a number of metabolic transformations, including hydrolysis by esterases or glucuronidases, oxidation by cytochrome P450 enzymes, reduction by glutathione reductase, or conjugation with glucuronic acid. 5-Bromo-8-fluoroquinoline boronic acid also specifically binds to markers expressed at high levels in Mycobacterium tuberculosis strains (e.g., ESX

• Marke: Biosynth

Chemische Eigenschaften

• Molekulargewicht: 269.87 g/mol
• Formel: C₉H₆BBrFNO₂
• Reinheit: Min. 95%