FGF 8 Human
Ref. 3D-CYT-087
| 2µg | 136,00 € | ||
| 10µg | 317,00 € |
Produktinformation
FGF 8 is a protein that is involved in the regulation of cell growth, differentiation and survival. It can bind to FGF receptors on cells, which triggers a signal transduction pathway. The activation of this pathway leads to the inhibition of GSK3β activity and the activation of Akt. FGF 8 also binds to FGFR4, which activates phospholipase C (PLC) and increases intracellular Ca2+. This leads to the activation of PKC and calpain, which then activate nitric oxide synthases (NOS). Activation of NOS leads to increased production of nitric oxide, which causes vasodilation.
FGF 8 has been shown to be an inhibitor for ion channels such as voltage-gated potassium channels and calcium-activated potassium channels. It also has been shown to inhibit receptor interactions such as binding with Ligands or Receptors.
Chemische Eigenschaften
Technische Anfrage zu: 3D-CYT-087 FGF 8 Human
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