1,4-Dithiothreitol

Ref. 3D-D-8200

Produktinformation

• Name: 1,4-Dithiothreitol
• Synonyme: DL-threo-2,3-Dihydroxy-1,4-dithiobutane DL-threo-1,4-Dimercapto-2,3-butanediol rac-Cleland’s Reagent

Beschreibung

Dithiothreitol, also known as DTT and Cleland’s reagent, is a broadly used disulfide reducing agent which finds application in the reduction of disulfide bridges in proteins. DTT is a fast, non-volatile solid and is less odorous than β-ME. DTT has a short half-life in water, requiring the preparation of fresh solutions every time. Furthermore, DTT must be used at neutral or basic pH due to the pKa values of the thiol moieties. DTT is a slightly more powerful reducing agent than its epimer DTE, due to the thiols trans to each other.

• Marke: Biosynth

Chemische Eigenschaften

• Molekulargewicht: 154.25 g/mol
• Formel: C₄H₁₀O₂S₂