3-hydroxy-2-naphthamide

CAS: 3665-51-8

Ref. 3D-DAA66551

Produktinformation

• Name: 3-hydroxy-2-naphthamide
• Synonyme: 2-Hydroxy-3-naphthalenecarboxamide, 2-Hydroxy-3-naphthamide, 2-Hydroxy-3-naphthoamide, 2-Hydroxy-3-naphthoic acid amide, 2-Naphthalenecarboxamide, 3-hydroxy-, 2-Naphthamide, 3-hydroxy-, 3-Hydroxy-2-naphthalenecarbamide, 3-Hydroxy-2-naphthalenecarboxamide, 3-Hydroxy-2-naphthamide, 3-Hydroxy-2-naphthoamide, 3-Hydroxynaphthalene-2-Carboxamide, Bon Acid Amide, NSC 37060

Beschreibung

3-Hydroxy-2-naphthamide is an antimycobacterial agent that inhibits the growth of bacteria by binding to the mycolic acid cell wall. It has been shown to have a higher affinity for Mycobacterium tuberculosis than other species of mycobacteria. 3-Hydroxy-2-naphthamide has also been shown to inhibit the production of reactive oxygen species (ROS) in Thp-1 cells and exhibits anti-inflammatory properties. The antimycobacterial activity of 3-hydroxy-2-naphthamide is due to its functional groups, which bind to the chloride ion and form a covalent bond. This reaction takes place in the presence of hydrochloric acid and proceeds with a reaction time of 2 hours at room temperature. The amido group acts as a leaving group during this reaction, forming an intramolecular hydrogen bond with the N atom in the amido group.

• Marke: Biosynth

Chemische Eigenschaften

• Molekulargewicht: 187.2 g/mol
• Formel: C₁₁H₉NO₂
• Reinheit: Min. 95%