N-Desmethyldoxylamine

CAS: 78868-03-8

Ref. 3D-DDA86803

Produktinformation

• Name: N-Desmethyldoxylamine
• Synonyme: Ethanamine, N-methyl-2-(1-phenyl-1-(2-pyridinyl)ethoxy)-, N-Methyl-2-(1-phenyl-1-(2-pyridinyl)ethoxy)ethanamine
• CAS: 78868-03-8

Beschreibung

N-Desmethyldoxylamine is a chemical with a molecular weight of 212.3 g/mol and a melting point of 114 °C. It has been shown to inhibit the growth of human cells in culture, as well as mouse liver cells, by inhibiting the formation of new blood vessels or angiogenesis. N-Desmethyldoxylamine is also used for the treatment of cancerous tumours in animals and humans. This drug binds to epidermal growth factor (EGF) receptors on cell surfaces and blocks the binding of EGF, which prevents cellular proliferation. N-Desmethyldoxylamine has been shown to cause side-chain cleavage reactions at the C2 position on the naphthalene ring and at the methyl group of the methoxy substituent on naphthalene. It can also be metabolized into an epoxide that reacts with DNA bases, leading to DNA damage and inhibition of transcriptional activity.

• Marke: Biosynth

Chemische Eigenschaften

• Molekulargewicht: 256.34 g/mol
• Formel: C₁₆H₂₀N₂O
• Reinheit: Min. 95%