PFI-1 (PF-6405761)

CAS: 1403764-72-6

Ref. 3D-DGC76472

Produktinformation

• Name: PFI-1 (PF-6405761)
• Synonyme: PF 6405761, 2-Methoxy-N-(3-methyl-2-oxo-1,2,3,4-tetrahydroquinazolin-6-yl)benzenesulfonamide, PFI 1, Benzenesulfonamide, 2-methoxy-N-(1,2,3,4-tetrahydro-3-methyl-2-oxo-6-quinazolinyl)-, 2-Methoxy-N-(1,2,3,4-tetrahydro-3-methyl-2-oxo-6-quinazolinyl)benzenesulfonamide

Beschreibung

PFI-1 is a protein inhibitor that inhibits transcriptional regulation through the inhibition of histone acetylation. PFI-1 has been shown to inhibit the replication of HIV and influenza A virus in vitro. PFI-1 binds to the acetylated lysine residues on histones, preventing their acetylation by HDACs and inhibiting transcriptional regulation. The mechanism of action for PFI-1 is not well understood, but it has been shown to inhibit proliferation of prostate cancer cells and may be a potential therapeutic agent for treatment of autoimmune diseases.

• Marke: Biosynth

Chemische Eigenschaften

• Molekulargewicht: 347.39 g/mol
• Formel: C₁₆H₁₇N₃O₄S
• Reinheit: Min. 95%