Produktinformation
AZD5069 is a molecule that has been shown to have potent inducers of chemokine production, and which is a potential anti-inflammatory agent. AZD5069 is also an inhibitor of the nuclear factor-kappaB (NF-κB) pathway and has been shown to be effective in patients with metastatic pancreatic cancer. The drug's clinical relevance as an anticancer therapeutic agent has been demonstrated by its ability to induce apoptosis in human myeloid leukemia cells. The drug inhibits the terminal half-life of high-sensitivity C reactive protein (hsCRP) in urine samples from patients with inflammatory diseases, indicating that it may be useful for treating such conditions. AZD5069 is orally bioavailable and has a pharmacokinetic profile suitable for oral administration. AZD5069 is a small molecule that is structurally related to other chemokines, such as SDF1, MCP1, MIP1α, and RANTES
Chemische Eigenschaften
Technische Anfrage zu: 3D-DKB38584 AZD5069
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