Azeliragon

CAS: 603148-36-3

Ref. 3D-DZA14836

Produktinformation

• Name: Azeliragon
• CAS: 603148-36-3

Beschreibung

Azeliragon is a microbial infection diagnostic agent that binds to the α7 nicotinic acetylcholine receptor. It has been shown to have low-dose efficacy in diabetic patients and long-term efficacy in prostate cancer cells. Azeliragon has also been used for treatment of inflammatory diseases such as rheumatoid arthritis. The molecule consists of an α7 nicotinic acetylcholine receptor-binding domain and a chemokine (CXCL13) binding domain, which interacts with toll-like receptor 4 (TLR4) on macrophages and other immune cells. Azeliragon binds to TLR4 and activates the immune system by activating macrophages and other cells, leading to increased production of cytokines such as IL-6, IL-8, TNFα, IL1β, CXCL9 and CXCL10. This can lead to fever, leukocytosis, lymphadenopathy and erythe

• Marke: Biosynth

Chemische Eigenschaften

• Molekulargewicht: 532.12 g/mol
• Formel: C₃₂H₃₈ClN₃O₂
• Reinheit: Min. 95%