3-Oxo-7α-hydroxy-5β-cholanoic acid

CAS: 4185-00-6

Ref. 3D-EAA18500

Produktinformation

• Name: 3-Oxo-7α-hydroxy-5β-cholanoic acid
• Synonyme: 5β-Cholanic acid, 7α-hydroxy-3-oxo-, (5β,7α)-7-Hydroxy-3-oxocholan-24-oic acid, 5β-Cholan-24-oic acid, 7α-hydroxy-3-oxo-, Cholan-24-oic acid, 7-hydroxy-3-oxo-, (5β,7α)-, 7α-Hydroxy-3-oxo-5β-cholanoic acid

Beschreibung

3-Oxo-7α-hydroxy-5β-cholanoic acid is a fatty acid that is an intermediate in the synthesis of bile acids. It is formed by the addition of hydroxyl groups to 7α, 12β-dihydroxycholesterol. The ethyl esters of 3-oxo-7α, 12β-dihydroxycholesterol are converted to 3-oxo-7α, 12β, 15β-, and 16β hydroxycholesterols by the action of bacteria such as Clostridium sp. or Propionibacterium sp. The formation of 3-oxo-7α, 12β, 15β-, and 16β hydroxycholesterols may be promoted by the presence of hydrochloric acid (HCl) or trifluoroacetic acid (TFA). 3OHDCA can be used for profiling human liver microsomes via HPLC analysis.

• Marke: Biosynth

Chemische Eigenschaften

• Molekulargewicht: 390.6 g/mol
• Formel: C₂₄H₃₈O₄
• Reinheit: Min. 95%