N-(Pyridin-2-yl)benzamide

CAS: 4589-12-2

Ref. 3D-EAA58912

Produktinformation

• Name: N-(Pyridin-2-yl)benzamide
• Synonyme: benzamide, N-2-pyridinyl-

Beschreibung

N-(Pyridin-2-yl)benzamide (NPA) is a ligand that selectively binds to the 5-HT1A receptor. It has been shown to inhibit 5-HT1A receptor mediated effects, such as maleate-induced contraction of rat ileum and inhibition of forskolin-stimulated cAMP production in rat pheochromocytoma cells. NPA has been used in pharmaceutical dosage forms and was found to be stable at pH 7.0 and 37°C, with a melting point of 162°C. In addition, it can be synthesized from 2-aminopyridine and benzoyl chloride by a cross coupling reaction. NPA is also used for the preparation of 5-HT1A receptor agonists.

• Marke: Biosynth

Chemische Eigenschaften

• Molekulargewicht: 198.22 g/mol
• Formel: C₁₂H₁₀N₂O
• Reinheit: Min. 95%