Ethynyl-phosphonic acid diethyl ester
CAS: 4851-51-8
Ref. 3D-EAA85151
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Produktinformation
Ethynyl-phosphonic acid diethyl ester is a heterocyclic compound that is synthesized by reacting 1,2-ethanedithiol with phosphoryl chloride. This molecule binds to histidine residues in the enzyme and inhibits its activity. The binding of the ester group to the enzyme leads to the formation of an acyclic nucleoside phosphonate that interacts with carboxylic acid groups on the enzyme surface. This interaction leads to a chemical change in the enzyme, which promotes nucleophilic attack on butyric acid. These reactions lead to a decrease in the levels of acetaldehyde, which is toxic and causes neurological disorders such as Alzheimer's disease.