Caspase substrate

CAS: 219138-02-0

Ref. 3D-EC58694

Produktinformation

• Name: Caspase substrate
• Synonyme: Z-Ile-Glu-Thr-Asp-AFCZ-IETD-AFC
• Marke: Biosynth
• Beschreibung: Caspase substrates are a class of pharmacological agents that regulate apoptosis. Caspases are proteases that cleave specific proteins in the cell, leading to apoptosis. Pro-apoptotic proteins activate caspases, while anti-apoptotic proteins inhibit them. Caspase substrates can be either pro-caspase or anti-caspase, depending on the desired effect. They may also be used to regulate caspases without affecting their activity. The caspase substrate is cleaved by caspases and releases a polypeptide fragment that triggers apoptosis in some cells, but not others. For example, the Hl-60 cell line is resistant to the pro-apoptotic effects of the substrate because it contains an anti-apoptotic protein called Bcl-2. In contrast, myocardial cells contain pro-apoptotic proteins and are sensitive to the pro-apoptotic effects of the substrate. In

Chemische Eigenschaften

• Molekulargewicht: 821.75 g/mol
• Reinheit: Min. 95%