(4-Methyl-2-thienyl)methylamine

CAS: 104163-39-5

Ref. 3D-EEA16339

Produktinformation

• Name: (4-Methyl-2-thienyl)methylamine
• Synonyme: (4-Methylthien-2-Yl)Methylamine, (4-Methylthien-2-yl)methanamine, (4-Methylthiophen-2-yl)methanamine, 1-(4-Methylthiophen-2-Yl)Methanamine, 2-(Aminomethyl)-4-Methylthiophene, 2-(Aminomethyl)-4-methylthiophene 97%, 2-Thiophenemethanamine, 4-methyl-, 4-Methyl-2-(Aminomethyl)Thiophene, 4-Methyl-2-thiophenemethanamine

Beschreibung

(4-Methyl-2-thienyl)methylamine is an inhibitor of protein kinases, which are enzymes that phosphorylate other proteins. It has been shown to have a high affinity for the dyrk1a protein and selectivity for this kinase over others. (4-Methyl-2-thienyl)methylamine also inhibits dyrk1a with a potency similar to that of ATP. The analogue of (4-methyl-2-thienyl)methylamine is more potent than the parent molecule at inhibiting dyrk1a. Docking studies show that (4-methyl-2-thienyl)methylamine binds in the active site of dyrk1a and prevents it from phosphorylating its substrate, leading to inhibition of cell growth in culture.

• Marke: Biosynth

Chemische Eigenschaften

• Molekulargewicht: 127.21 g/mol
• Formel: C₆H₉NS
• Reinheit: Min. 95%