4-Methylumbelliferyl a-L-idopyranosiduronic acid 2-sulphate disodium salt - Moscerdam™ biochemical purity

CAS: 1045020-74-3

Ref. 3D-EM03201

Produktinformation

• Name: 4-Methylumbelliferyl a-L-idopyranosiduronic acid 2-sulphate disodium salt - Moscerdam™ biochemical purity
• Synonyme: 4-MU-a-IdoA 2-sulfate4MU-a-L-iduronide-2-sulphate NaM2
• CAS: 1045020-74-3

Beschreibung

PAIRED PRODUCT AVAILABLE: alpha-L-iduronidase Enzyme, FI179383
4MU-alpha-L-iduronide-2-sulphate is a fluorogenic substrate for iduronate-2-sulphatase (IDS), used in a 2-step assay coupled with alpha-L-iduronidase. The assay is used in biochemical testing for Hunter syndrome (mucopolysaccharidosis II / MPS II). In a first step, iduronidate-2-sulphatase from biological samples cleaves the sulphate group from 4MU-alpha-L-iduronide-2-sulphate. In a second step, exogeneous alpha-L-iduronidase which cleaves the 4-MU moiety is added to the reaction, resulting in release of a fluorescent signal (Ex 360 nm / Em 455 nm). The reaction is stopped by the addition of sodium carbonate.

• Marke: Biosynth

Chemische Eigenschaften

• Molekulargewicht: 476.32 g/mol
• Formel: C₁₆H₁₄Na₂O₁₂S
• Reinheit: Min. 99 Area-%
• Farbe/Form: White Powder