4-Methylumbelliferyl N,N',N'',N'''-tetraacetyl-b-D-chitotetraoside

CAS: 53643-14-4

Ref. 3D-EM04831

Produktinformation

• Name: 4-Methylumbelliferyl N,N',N'',N'''-tetraacetyl-b-D-chitotetraoside
• Synonyme: GlcNAc1-b-4GlcNAc1-b-4GlcNAc1-b-4GlcNAc1-b-4MU
• Marke: Biosynth
• Beschreibung: 4-Methylumbelliferyl N,N',N'',N'''-tetraacetyl-beta-D-chitotetraoside is a fluorogenic substrate for chitinase. After enzymatic cleaveage, free 4-methylumbelliferone (also known as hymecromone) is released, exhibiting blue fluorescence upon excitation with UV light. The strongest fluorescence of 4-methylumbelliferone requires deprotonation of the hydroxyl group (thus requires alkaline pH), with a maximal fluorescence intensity obtained with excitation at 350 to 370 nm and emission at 440 to 470 nm. The use of 4-methylumbelliferyl N,N',N'',N'''-tetraacetyl-beta-D-chitotetraosideas a substrate for measuring the chitinase activity is used for fungal infection detection and Gaucher disease screening.

Chemische Eigenschaften

• Molekulargewicht: 988.94 g/mol
• Formel: C₄₂H₆₀N₄O₂₃
• Reinheit: Min. 95%
• Farbe/Form: Powder