4-Methylumbelliferyl 6-thio-palmitate-b-D-glucopyranoside - Moscerdam™ biochemical purity

CAS: 229644-17-1

Ref. 3D-EM06650

Produktinformation

• Name: 4-Methylumbelliferyl 6-thio-palmitate-b-D-glucopyranoside - Moscerdam™ biochemical purity
• Synonyme: Mu-6S-Palm-b-GlcINCL
• Marke: Biosynth
• Beschreibung: 4-Methylumbelliferyl 6-thio-palmitate-b-D-glucopyranoside (Mu-6S-Palm-β-Glc) is a fluorogenic substrate of palmitoyl-protein thioesterase 1 (PPT1), used in the diagnosis of infantile neuronal ceroid lipofuscinosis (INCL). INCL, also known as infantile CLN1 disease, is a rapidly progressing lysosomal storage disorder (LSD), caused by a deficiency of PPT1. Mu-6S-Palm-β-Glc is also used as the substrate in the PPT assay to investigate the retention of lysosomal enzyme activity of bi-functional IgG-PPT1 fusion protein in the delivery across blood-brain barrier.

Chemische Eigenschaften

• Molekulargewicht: 592.78 g/mol
• Formel: C₃₂H₄₈O₈S
• Reinheit: Min. 95%
• Farbe/Form: White Powder