4-Methylumbelliferyl N-acetyl-a-D-neuraminic acid ammonium

CAS: 206442-98-0

Ref. 3D-EM09053

Produktinformation

• Name: 4-Methylumbelliferyl N-acetyl-a-D-neuraminic acid ammonium
• Marke: Biosynth
• Beschreibung: 4-Methylumbelliferyl N-acetyl-alpha-D-neuraminic acid ammonium is a fluorogenic substrate for neuraminidase. After enzymatic cleaveage, free 4-methylumbelliferone (also known as hymecromone) is released, exhibiting blue fluorescence upon excitation with UV light. The strongest fluorescence of 4-methylumbelliferone requires deprotonation of the hydroxyl group (thus requires alkaline pH), with a maximal fluorescence intensity obtained with excitation at 350 to 370 nm and emission at 440 to 470 nm. The use of 4-methylumbelliferyl N-acetyl-alpha-D-neuraminic acid ammoniumas a substrate for measuring the neuraminidase activity is used for detecting the glycoproteins on the surface of influenza A and B viruses, as well as for sialidosis diagnosis.

Chemische Eigenschaften

• Molekulargewicht: 471.44 g/mol
• Formel: C₂₁H₂₈N₂O₁₁
• Reinheit: Min. 95%
• Farbe/Form: Powder