6-Methyl-2-pyridyl 2-acetamido-2-deoxy-b-D-thioglucopyranoside

CAS: 149263-94-5

Ref. 3D-EM10847

Produktinformation

• Name: 6-Methyl-2-pyridyl 2-acetamido-2-deoxy-b-D-thioglucopyranoside
• Synonyme: 6-Methyl-2-pyridyl N-acetyl-b-D-thioglucosamineMPT-NAG, Mpt-Nag, 6-methyl-2-pyridinyl-2-(acetylamino)-2-deoxy-1-thio-β-D-glucopyranoside, 6-Methyl-2-pyridinyl 2-(acetylamino)-2-deoxy-1-thio-beta-D-glucopyranoside

Beschreibung

The 6-Methyl-2-pyridyl 2-acetamido-2-deoxy-b-D-thioglucopyranoside is a chloride salt that has been used in the laboratory to develop an analytical method for the determination of glucose in urine samples. The bioavailability of 6MP is low and it is excreted by renal filtration, so this compound has been used as a marker for renal transplantation. Glomerular filtration rate (GFR) is reduced in diabetic patients, leading to a decrease in the amount of 6MP excreted. This drug can be administered orally or intravenously and has shown efficacy at low dose levels. Low doses have also been associated with decreased detection sensitivity due to its low level of excretion, which makes it an ideal candidate for use as a biomarker for chronic kidney disease. A chronic kidney disease animal model was used to study the effects on GFR and creatinine clearance rates

• Marke: Biosynth

Chemische Eigenschaften

• Molekulargewicht: 328.39 g/mol
• Reinheit: Min. 95%
• Farbe/Form: White Powder