4-Methylumbelliferyl-2-O-(α-L-fucopyranosyl)-β-L-fucopyranoside

Ref. 3D-EM170834

Produktinformation

• Name: 4-Methylumbelliferyl-2-O-(α-L-fucopyranosyl)-β-L-fucopyranoside
• Marke: Biosynth
• Beschreibung: 4-Methylumbelliferyl-2-O-(alpha-L-fucopyranosyl)-beta-L-fucopyranoside is a fluorogenic substrate for alpha-L-fucosidase. After enzymatic cleaveage, free 4-methylumbelliferone (also known as hymecromone) is released, exhibiting blue fluorescence upon excitation with UV light. The strongest fluorescence of 4-methylumbelliferone requires deprotonation of the hydroxyl group (thus requires alkaline pH), with a maximal fluorescence intensity obtained with excitation at 350 to 370 nm and emission at 440 to 470 nm. The use of 4-methylumbelliferyl-2-O-(alpha-L-fucopyranosyl)-beta-L-fucopyranosideas a substrate for measuring the alpha-L-fucosidase activity is used for diagnosis of fucosidosis (defficiency of L-fucosidase).

Chemische Eigenschaften

• Molekulargewicht: 468.45 g/mol
• Reinheit: Min. 95%
• Farbe/Form: White/Off-White Solid