4-Methylumbelliferyl phosphate dilithium

CAS: 125328-83-8

Ref. 3D-EM52229

Produktinformation

• Name: 4-Methylumbelliferyl phosphate dilithium
• Synonyme: 4-Mu-Phos·2Li
• Marke: Biosynth
• Beschreibung: 4-Methylumbelliferyl phosphate dilithium is a fluorogenic substrate for alkaline phosphatase. After enzymatic cleaveage, free 4-methylumbelliferone (also known as hymecromone) is released, exhibiting blue fluorescence upon excitation with UV light. The strongest fluorescence of 4-methylumbelliferone requires deprotonation of the hydroxyl group (thus requires alkaline pH), with a maximal fluorescence intensity obtained with excitation at 350 to 370 nm and emission at 440 to 470 nm. The use of 4-methylumbelliferyl phosphate dilithiumas a substrate for measuring the alkaline phosphatase activity is used for bone metabolism disorder studies and hypophosphatasia diagnosis.

Chemische Eigenschaften

• Molekulargewicht: 268.01 g/mol
• Formel: C₁₀H₇O₆P•Li₂
• Reinheit: Min. 95%
• Farbe/Form: Powder