4-Methylumbelliferyl pyrophosphate diester disodium salt

CAS: 84282-11-1

Ref. 3D-EM52292

Produktinformation

• Name: 4-Methylumbelliferyl pyrophosphate diester disodium salt
• Synonyme: Bis(4-methylumbelliferyl)pyrophosphoric acid disodium salt
• Marke: Biosynth
• Beschreibung: 4-Methylumbelliferyl pyrophosphate diester disodium salt is a fluorogenic substrate for pyrophosphatases or diphosphatases. After enzymatic cleaveage, free 4-methylumbelliferone (also known as hymecromone) is released, exhibiting blue fluorescence upon excitation with UV light. The strongest fluorescence of 4-methylumbelliferone requires deprotonation of the hydroxyl group (thus requires alkaline pH), with a maximal fluorescence intensity obtained with excitation at 350 to 370 nm and emission at 440 to 470 nm. The use of 4-methylumbelliferyl pyrophosphate diester disodium saltas a substrate for measuring the pyrophosphatases or diphosphatases activity is used for monitoring and diagnosis of pyrophosphatase deficiency and bone metabolism disorder.

Chemische Eigenschaften

• Molekulargewicht: 538.25 g/mol
• Formel: C₂₀H₁₄Na₂O₁₁P₂
• Reinheit: Min. 95%
• Farbe/Form: White Powder