BAY 12-17389

CAS: 1554458-53-5

Ref. 3D-EMC45853

Produktinformation

• Name: BAY 12-17389
• Synonyme: N-Cyclopropyl-4-[6-(2,3-difluoro-4-methoxyphenoxy)-8-[(3,3,3-trifluoropropyl)amino]imidazo[1,2-b]pyridazin-3-yl]-2-methylbenzamide

Beschreibung

BAY 12-17389 is a novel anticancer drug that inhibits the activity of CDK4 and CDK6. It is an imidazopyrazine derivative, which binds to the ATP-binding pocket of the enzyme, thereby preventing its activation. BAY 12-17389 has shown anticancer activity in animal models for skin cancer and bladder cancer. In vitro assays have demonstrated that BAY 12-17389 is effective at inhibiting proliferation of cultured cells from different types of human cancers. The effective dose for BAY 12-17389 is not yet known but it has been shown to be safe at doses as high as 2 µM.

• Marke: Biosynth

Chemische Eigenschaften

• Molekulargewicht: 561.5 g/mol
• Formel: C₂₇H₂₄F₅N₅O₃
• Reinheit: Min. 95%