2-Naphthyl-β-D-Glucuronide Sodium Salt

CAS: 20838-64-6

Ref. 3D-EN03259

Produktinformation

• Name: 2-Naphthyl-β-D-Glucuronide Sodium Salt
• Synonyme: b-Nap-b-D-GlcA.Na
• Marke: Biosynth
• Beschreibung: 2-Naphthyl-beta-D-glucuronide sodium salt is an enzyme substrate to detect beta-glucuronidase. The enzyme cleaves the glycosidic bond in 2-naphthyl-beta-D-glucuronide to release 2-naphtol and glucuronic acid. Beta-glucuronidase activity assays are important in many fields such as cancer research, as the enzyme is expressed in some tumors and its activity can be targeted for cancer therapy. The enzyme has also an important role in drug metabolism as it recognizes and binds to drug glucuronide conjugate (as 2-naphthyl-beta-D-glucuronide) facilitating its hydrolysis to release the active part. 2-Naphthyl-beta-D-glucuronide sodium salt has a higher solubility as it is in its salt form.

Chemische Eigenschaften

• Molekulargewicht: 342.28 g/mol
• Formel: C₁₆H₁₅NaO₇
• Reinheit: Min. 95%
• Farbe/Form: Powder