N-Desmethyl imatinib mesylate

CAS: 404844-03-7

Ref. 3D-ERA84403

Produktinformation

• Name: N-Desmethyl imatinib mesylate
• Synonyme: Benzamide, N-[4-methyl-3-[[4-(3-pyridinyl)-2-pyrimidinyl]amino]phenyl]-4-(1-piperazinylmethyl)-, monomethanesulfonate, CGP 74588, Benzamide, N-[4-methyl-3-[[4-(3-pyridinyl)-2-pyrimidinyl]amino]phenyl]-4-(1-piperazinylmethyl)-, methanesulfonate (1:1)

Beschreibung

N-Desmethyl imatinib mesylate is an active metabolite of Imatinib Mesylate, a drug used to treat metastatic colorectal cancer. The compound is an inhibitor of the tyrosine kinase activity of the epidermal growth factor receptor (EGFR) and is taken orally. N-Desmethyl imatinib mesylate has been shown to be effective in women with metastatic colorectal cancer, producing a hematologic response in 67% of patients. This compound has also been found to have a longer half-life than Imatinib Mesylate and may be used as a substitute for this drug in women with metastatic colorectal cancer who are unable to take oral medications.

• Marke: Biosynth

Chemische Eigenschaften

• Molekulargewicht: 575.7 g/mol
• Formel: C₂₉H₃₃N₇O₄S
• Reinheit: Min. 95%