GS 9973

CAS: 1229208-44-9

Ref. 3D-EZB20844

Produktinformation

• Name: GS 9973
• Synonyme: 6-(1H-Indazol-6-yl)-N-(4-morpholinophenyl)imidazo[1,2-a]pyrazin-8-amine, Imidazo[1,2-a]pyrazin-8-amine, 6-(1H-indazol-6-yl)-N-[4-(4-morpholinyl)phenyl]-, 6-(1H-Indazol-6-yl)-N-[4-(4-morpholinyl)phenyl]imidazo[1,2-a]pyrazin-8-amine, Entospletinib

Beschreibung

GS 9973 is a research drug that inhibits the activity of protein kinases, which are enzymes that regulate the function of other proteins. GS 9973 inhibits the activity of mcl-1, an effector protein in the apoptosis pathway and is currently being tested for its ability to inhibit cancer cells from spreading. GS 9973 has been shown to have a low risk of toxicity in humans and has been found to be safe for use in clinical trials with human pharmacokinetics. This drug also inhibits P-gp substrates, which prevents it from entering into the retina. The only side effects observed so far are eye disorders such as conjunctivitis and iritis.

• Marke: Biosynth

Chemische Eigenschaften

• Molekulargewicht: 411.47 g/mol
• Formel: C₂₃H₂₁N₇O
• Reinheit: Min. 95%